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Unexplained weight loss can occasionally be a sign of cancer learn about other potential cancer symptoms and the many other causes of unexplained weight loss. Weight loss cancer pathophysiology. Unexplained weight loss has many causes, medical and nonmedical often, a combination of things results in a general decline in your health and a related weight loss sometimes a specific cause isn't found usually, an unrecognized cancer will have other symptoms or abnormalities of laboratory tests, in addition to unexplained weight loss.

weight loss cancer pathophysiology

Figure 2

Cachexia is a complex mechanism that causes weight loss in cancer patients the condition causes decreased appetite, which in turn has your body looking at itself for nutrition in this we see loss of fat stores and loss of muscle mass, along with increasing fatigue this becomes a terrible, vicious cycle in. Introduction. the pathophysiology of cancer anorexia cachexia is driven by a variable combination of reduced food intake and abnormal metabolism that leads to a negative protein and energy balance (figure 1). 1, 2. there has been great progress in understanding the underlying mechanisms of cachexia and recent literature reports that many of the primary events driving cancer anorexia cachexia. Why do weight and muscle loss happen? one cause is the cancer itself. for example, in an effort to fight the cancer, the body produces substances called cytokines. these substances can lead to weight loss, muscle loss, and a decrease in appetite. another common cause is the treatments for cancer..

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